Natalizumab (Tysabri) Prior Authorization Request for Multiple Sclerosis

Streamline Your Natalizumab Prior Authorization Process

Natalizumab (Tysabri) infusion therapy represents a critical treatment option for patients with relapsing forms of multiple sclerosis (MS), particularly those who have shown inadequate response to or cannot tolerate other disease-modifying therapies. However, securing insurance approval requires comprehensive documentation of disease activity, clinical justification, and critical safety monitoring data.

This Natalizumab Prior Authorization Request Form is designed specifically for neurologists, MS specialists, and healthcare administrative staff who regularly submit prior authorization requests for this high-efficacy therapy. Built on Paperform, this template captures all essential clinical data points that payers require—from detailed disease history and EDSS scores to MRI findings, JCV antibody testing results, and previous treatment failures.

Why This Template Works for Neurology Practices

Rather than piecing together information from multiple sources or wrestling with insurance company PDFs, this digital form allows your clinical team to complete comprehensive prior authorization requests efficiently. The structured format ensures you don't miss critical elements like specific MRI findings showing new or enhancing lesions, documented relapse history, or the essential JCV antibody stratification that determines PML risk.

The form intelligently adapts based on responses—for instance, expanding to capture details about previous DMTs when treatment history is indicated—ensuring you provide exactly the documentation needed without unnecessary complexity.

Automate Your Authorization Workflow with Stepper

Once submitted, this form can integrate seamlessly with your practice workflow using Stepper, Paperform's AI-native workflow automation platform. You can automatically route completed authorizations to billing staff for submission, create follow-up tasks for checking authorization status, sync patient information to your EHR system, and trigger reminder notifications when JCV antibody testing needs to be updated. This transforms a typically manual, time-consuming process into a streamlined operation.

Built for Healthcare Teams Who Value Efficiency

Neurology practices, MS clinics, and infusion centers trust Paperform to handle sensitive healthcare workflows with SOC 2 Type II compliance and robust data security. While not HIPAA compliant, Paperform provides the professional-grade infrastructure and integrations needed to manage prior authorization documentation efficiently, reducing delays in therapy initiation and improving patient outcomes.

Whether you're managing a high-volume MS clinic or a smaller specialty practice, this template adapts to your needs—collecting the clinical evidence payers demand while respecting the time constraints of busy healthcare providers.